Nasser Rabie Ahmed El-Brollosy

Publications

List of Publications

Synthesis and Antiviral Evaluation of 1-[(2-Phenoxyethyl) oxymethyl] and 6-(3,5-Dimethoxybenzyl) Analogues of HIV Drugs Emivirine and TNK-651 ,July 2015

Publisher

Drug Research

Research Type

مشترك

Date of acceptance

Publishing Date

7/31/2015

Google Scholar

Abstract

Vibrational spectroscopic (FT-IR and FT-Raman) studies, HOMO–LUMO, NBO analysis and MEP of 6-methyl-1-({[(2E)-2-methyl-3-phenyl-prop-2-en-1-yl] oxy} methyl)-1, 2, 3, 4-tetra-hydroquinazoline-2, 4-dione, a potential chemotherapeutic agent, using density functional methods ,January 2015

Publisher

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Research Type

مشترك

Date of acceptance

Publishing Date

1/5/2015

Google Scholar

Abstract

Molecular structure and vibrational spectra of 2-Ethoxymethyl-6-ethyl-2, 3, 4, 5-tetrahydro-1, 2, 4-triazine-3, 5-dione, a potential chemotherapeutic agent, by density functional methods ,December 2014

Publisher

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Research Type

مشترك

Date of acceptance

Publishing Date

12/10/2014

Google Scholar

Abstract

Theoretical investigations on the molecular structure, vibrational spectra, HOMO–LUMO analyses and NBO study of 1-[(Cyclopropylmethoxy) methyl]-5-ethyl-6-(4-methylbenzyl)-1, 2, 3, 4-tetrahydropyrimidine-2, 4-dione ,December 2014

Publisher

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Research Type

مشترك

Date of acceptance

Publishing Date

12/10/2014

Google Scholar

Abstract

Vibrational spectra, NBO analysis, HOMO–LUMO and first hyperpolarizability of 2-{[(2-Methylprop-2-en-1-yl) oxy] methyl}-6-phenyl-2, 3, 4, 5-tetrahydro-1, 2, 4-triazine-3, 5-dione, a potential chemotherapeutic agent based on density functional theory calculations ,December 2014

Publisher

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Research Type

مشترك

Date of acceptance

Publishing Date

12/10/2014

Google Scholar

Abstract

Antimicrobial pyrimidinones II: synthesis and antimicrobial evaluation of certain novel 5, 6-disubstituted 2-(substituted amino) alkylthiopyrimidin-4 (3H)-ones ,November 2014

Publisher

Monatshefte für Chemie-Chemical Monthly

Research Type

مشترك

Date of acceptance

Publishing Date

11/1/2014

Google Scholar

Abstract

Unusual Sulfuric Acid-Induced Thiol Oxidation on Dehydrative Cyclization of Potassium N′-(1-Adamantylcarbonyl) Dithiocarbazate at Room Temperature ,April 2014

Publisher

Phosphorus, Sulfur, and Silicon and the Related Elements

Research Type

مشترك

Date of acceptance

Publishing Date

4/3/2014

Google Scholar

Abstract

Synthesis, Single Crystal X-Ray Structure, and Antimicrobial Activity of 6-(1, 3-Benzodioxol-5-ylmethyl)-5-ethyl-2-{[2-(morpholin-4-yl) ethyl] sulfanyl} pyrimidin-4 (3H)-one ,January 2014

Publisher

Journal of Chemistry

Research Type

مشترك

Date of acceptance

Publishing Date

1/1/2014

Google Scholar

Abstract

Pyrimidine-5-carbonitriles II: synthesis and antimicrobial activity of novel 6-alkyl-2, 4-disubstituted pyrimidine-5-carbonitriles ,January 2014

Publisher

Drug research

Research Type

مشترك

Date of acceptance

Publishing Date

1/1/2014

Google Scholar

Abstract

Synthesis of novel 2-(substituted amino) alkylthiopyrimidin-4 (3H)-ones as potential antimicrobial agents ,December 2013

Publisher

Molecules

Research Type

مشترك

Date of acceptance

Publishing Date

12/27/2013

Google Scholar

Abstract

Pyrimidine-5-carbonitriles–part III: synthesis and antimicrobial activity of novel 6-(2-substituted propyl)-2, 4-disubstituted pyrimidine-5-carbonitriles ,December 2013

Publisher

Heterocyclic Communications

Research Type

مشترك

Date of acceptance

Publishing Date

12/1/2013

Google Scholar

Abstract

4-Benzyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-1, 2, 4-triazole-5-thione ,May 2013

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

5/1/2013

Google Scholar

Abstract

N′-(Adamantan-2-ylidene) benzohydrazide ,July 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2012

Google Scholar

Abstract

5-(Adamantan-1-yl)-3-[(4-benzylpiperazin-1-yl) methyl]-1, 3, 4-oxadiazole-2 (3H)-thione ,July 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2012

Google Scholar

Abstract

3-(Adamantan-1-yl)-4-[(E)-(2, 6-difluorobenzylidene) amino]-1-[(4-phenylpiperazin-1-yl) methyl]-1H-1, 2, 4-triazole-5 (4H)-thione ,July 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2012

Google Scholar

Abstract

2-[(4-Chlorobenzyl) sulfanyl]-4-(2-methylpropyl)-6-[3-(trifluoromethyl) anilino] pyrimidine-5-carbonitrile ,July 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2012

Google Scholar

Abstract

2-Benzylsulfanyl-4-[(4-methylphenyl) sulfanyl]-6-pentylpyrimidine-5-carbonitrile ,July 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2012

Google Scholar

Abstract

2-[(Cyclohex-3-en-1-ylmethoxy) methyl]-6-phenyl-1, 2, 4-triazine-3, 5 (2H, 4H)-dione ,June 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

6/1/2012

Google Scholar

Abstract

5-Methoxy-2-[(5-methoxy-1H-indol-1-yl) carbonyl]-1H-indole ,June 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

6/1/2012

Google Scholar

Abstract

1-{[(2, 3-Dihydro-1H-inden-2-yl) oxy] methyl} quinazoline-2, 4 (1H, 3H)-dione ,June 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

6/1/2012

Google Scholar

Abstract

1-{(E)-[3-(1H-Imidazol-1-yl)-1-(4-methoxyphenyl) propylidene] amino}-3-(2-methylphenyl) urea ,June 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

6/1/2012

Google Scholar

Abstract

1-{(E)-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene] amino}-3-(2-methylphenyl) urea ,June 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

6/1/2012

Google Scholar

Abstract

6-Chloro-1-({[(2E)-2-methyl-3-phenylprop-2-en-1-yl] oxy} methyl)-1, 2, 3, 4-tetrahydroquinazoline-2, 4-dione ,June 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

6/1/2012

Google Scholar

Abstract

1-(Adamantan-1-yl)-3-(4-fluorophenyl) thiourea ,May 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

5/1/2012

Google Scholar

Abstract

3-(1-Adamantyl)-4-amino-1-(2-benzoyl-1-phenylethyl)-1H-1, 2, 4-triazol-5 (4H)-thione ,May 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

5/1/2012

Google Scholar

Abstract

2-[(2-Methoxyethyl) sulfanyl]-4-(2-methylpropyl)-6-oxo-1, 6-dihydropyrimidine-5-carbonitrile ,May 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

5/1/2012

Google Scholar

Abstract

3-(Adamantan-1-yl)-4-ethyl-1H-1, 2, 4-triazole-5 (4H)-thione ,May 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

5/1/2012

Google Scholar

Abstract

6-(3, 5-Dimethylbenzyl)-5-ethyl-1-[(2-phenylethoxy) methyl] pyrimidine-2, 4 (1H, 3H) dione ,April 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

4/1/2012

Google Scholar

Abstract

5-Methoxy-1-[(5-methoxy-1H-indol-2-yl) methyl]-1H-indole ,April 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

4/1/2012

Google Scholar

Abstract

4-Benzyl-N-methylpiperazine-1-carbothioamide ,March 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

3/1/2012

Google Scholar

Abstract

2-(Adamantan-1-yl)-5-(4-nitrophenyl)-1, 3, 4-oxadiazole ,March 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

3/1/2012

Google Scholar

Abstract

1-[(Cyclopropylmethoxy) methyl]-5-ethyl-6-(4-methylbenzyl)-1, 2, 3, 4-tetrahydropyrimidine-2, 4-dione ,February 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

2/1/2012

Google Scholar

Abstract

1-[(Cyclopropylmethoxy) methyl]-6-(3, 4-dimethoxybenzyl)-5-ethyl-1, 2, 3, 4-tetrahydropyrimidine-2, 4-dione ethanol hemisolvate ,February 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

2/1/2012

Google Scholar

Abstract

2-Ethoxymethyl-6-ethyl-2, 3, 4, 5-tetrahydro-1, 2, 4-triazine-3, 5-dione ,February 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

2/1/2012

Google Scholar

Abstract

6-(3, 5-Dimethylbenzyl)-5-ethyl-1-[(3-phenylpropoxy) methyl]-1, 2, 3, 4-tetrahydropyrimidine-2, 4-dione ,February 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

2/1/2012

Google Scholar

Abstract

2-{[(2-Methylprop-2-en-1-yl) oxy] methyl}-6-phenyl-2, 3, 4, 5-tetrahydro-1, 2, 4-triazine-3, 5-dione ,February 2012

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

2/1/2012

Google Scholar

Abstract

6-(3, 5-Dimethylbenzyl)-5-ethyl-1-[(2-phenoxyethoxy) methyl]-1, 2, 3, 4-tetrahydropyrimidine-2, 4-dione ,November 2011

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

11/1/2011

Google Scholar

Abstract

Synthesis and antimicrobial activity of some novel 5-alkyl-6-substituted uracils and related derivatives ,June 2011

Publisher

Molecules

Research Type

مشترك

Date of acceptance

Publishing Date

6/8/2011

Google Scholar

Abstract

Some observations on the base-catalyzed cyclocondensation of 2, 6-dihalobenzaldehydes, ethyl cyanoacetate, and thiourea ,April 2010

Publisher

Synthetic Communications

Research Type

مشترك

Date of acceptance

Publishing Date

4/26/2010

Google Scholar

Abstract

Synthesis of Novel Uracil Non‐Nucleoside Derivatives as Potential Reverse Transcriptase Inhibitors of HIV‐1 ,November 2009

Publisher

Archiv der Pharmazie

Research Type

مشترك

Date of acceptance

Publishing Date

11/1/2009

Google Scholar

Abstract

Synthesis and antimicrobial evaluation of 6-azauracil non-nucleosides ,December 2008

Publisher

Monatshefte für Chemie-Chemical Monthly

Research Type

منفرد

Date of acceptance

Publishing Date

12/1/2008

Google Scholar

Abstract

Synthesis and Antiviral Evaluation of 6‐(Trifluoromethylbenzyl) and 6‐(Fluorobenzyl) Analogues of HIV Drugs Emivirine and GCA‐186 ,January 2008

Publisher

Archiv der Pharmazie

Research Type

مشترك

Date of acceptance

Publishing Date

1/1/2008

Google Scholar

Abstract

Synthesis of new quinazoline-2, 4 (1H, 3H)-dione non-nucleoside analogues of the reverse transcriptase inhibitor TNK-651 ,June 2007

Publisher

Journal of Chemical Research

Research Type

منفرد

Date of acceptance

Publishing Date

6/1/2007

Google Scholar

Abstract

Synthesis of novel uracil non-nucleosides analogues of 3, 4-dihydro-2-alkylthio-6-benzyl-4-oxopyrimidines and 6-benzyl-1-ethoxymethyl-5-isopropyluracil ,May 2007

Publisher

Journal of Chemical Research

Research Type

مشترك

Date of acceptance

Publishing Date

5/1/2007

Google Scholar

Abstract

Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1, 3, 4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1, 3, 4-thiadiazoles ,February 2007

Publisher

European journal of medicinal chemistry

Research Type

مشترك

Date of acceptance

Publishing Date

2/1/2007

Google Scholar

Abstract

dihydropyrimidine-5-carbonitrile ,November 2005

Publisher

Acta Crystallographica Section E: Structure Reports Online

Research Type

مشترك

Date of acceptance

Publishing Date

11/1/2005

Google Scholar

Abstract

Synthesis of 6‐(3, 5‐Dichlorobenzyl) Derivatives as Isosteric Analogues of the HIV Drug 6‐(3, 5‐Dimethylbenzyl)‐1‐(ethoxymethyl)‐5‐isopropyluracil (GCA‐186) ,July 2005

Publisher

Archiv der Pharmazie

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2005

Google Scholar

Abstract

Synthesis of N-1-(Indanyloxymethyl) and N-1-(4-Hydroxybut-2-enyloxymethyl) Analogues of the HIV Drugs Emivirine and GCA-186 ,July 2005

Publisher

Monatshefte für Chemie/Chemical Monthly

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2005

Google Scholar

Abstract

Synthesis of 6-arylvinyl analogues of the HIV drugs SJ-3366 and Emivirine ,March 2004

Publisher

Bioorganic & medicinal chemistry

Research Type

مشترك

Date of acceptance

Publishing Date

3/1/2004

Google Scholar

Abstract

Anti-retroviral 5,6-disubstituted acycloprymidine nucleoside derivatives ,July 2003

Publisher

PCT, WO 03/057677

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2003

Google Scholar

Abstract

Synthesis of Novel MKC‐442 Analogues with Potent Activities against HIV‐1 ,July 2003

Publisher

Archiv der Pharmazie

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2003

Google Scholar

Abstract

Synthesis of new uracil non‐nucleoside derivatives as potential inhibitors of HIV‐1 ,March 2003

Publisher

Journal of heterocyclic chemistry

Research Type

مشترك

Date of acceptance

Publishing Date

3/1/2003

Google Scholar

Abstract

Synthesis of some novel N-glycosyl amines from aminoquinazolin- 4(3H)-ones derivatives ,January 2003

Publisher

AFINIDAD

Research Type

مشترك

Date of acceptance

Publishing Date

1/1/2003

Google Scholar

Abstract

Synthesis of Novel Quinazoline Derivatives for Potential Anticancer Activity ,January 2003

Publisher

ALEXANDRIA JOURNAL OF PHARMACEUTICAL SCIENCES

Research Type

مشترك

Date of acceptance

Publishing Date

1/1/2003

Google Scholar

Abstract

Synthesis of novel N-1 (allyloxymethyl) analogues of 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, emivirine) with improved activity against HIV-1 and its mutants ,December 2002

Publisher

Journal of medicinal chemistry

Research Type

مشترك

Date of acceptance

Publishing Date

12/19/2002

Google Scholar

Abstract

A facile and efficient synthesis of novel 1, 2, 4-triazolo [5, 1-b] quinazolin-9-one derivatives ,September 2001

Publisher

Monatshefte für Chemie/Chemical Monthly

Research Type

مشترك

Date of acceptance

Publishing Date

9/1/2001

Google Scholar

Abstract

Synthesis and reactions of some new 1, 2, 4-triazine derivatives of biological interest ,August 2000

Publisher

Phosphorus, Sulfur, and Silicon and the Related Elements

Research Type

منفرد

Date of acceptance

Publishing Date

8/1/2000

Google Scholar

Abstract

Synthesis and Characterization of Manganese (II), Nickel (II) and Copper (II) Complexes of 4-(Arylideneamino)-3-Mercapto-6-Methyl-1, 2, 4-Triazin-5 (4H)-Ones ,July 2000

Publisher

Sythesis and Reactivity in Inorganic and Matel-Organic Chemistry

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/2000

Google Scholar

Abstract

Ring-opening mechanism in the glycosylation of 2, 4 (1H, 3H)-quinazolinediones with erythro-3-O-tosyl and threo-3-iodo-2, 3-dideoxypentofuranosides ,January 1996

Publisher

Bulletin de la Société chimique de France

Research Type

مشترك

Date of acceptance

Publishing Date

1/1/1996

Google Scholar

Abstract

Synthesis of 3'-Azido, 3'Amino, and 2', 3'-Dideoxy Nucleosides from Thieno [2, 3-d] Pyrimidine-2, 4 (1H, 3H)-Dione ,January 1996

Publisher

SULFUR LETTERS

Research Type

مشترك

Date of acceptance

Publishing Date

1/1/1996

Google Scholar

Abstract

Synthesis and antiviral evaluation of quinazoline, thieno‐[2, 3‐d] pyrimidine, and lumazine analogues of 3′‐fluoro‐3′‐deoxythymidine (FLT) ,July 1995

Publisher

European Journal of Organic Chemistry

Research Type

مشترك

Date of acceptance

Publishing Date

7/1/1995

Google Scholar

Abstract

Synthesis of 5′‐azido‐and 5′‐amino‐2′, 5′‐dideoxynucleosides from quinazoline‐2, 4 (1H, 3H)‐diones ,May 1995

Publisher

Journal of heterocyclic chemistry

Research Type

مشترك

Date of acceptance

Publishing Date

5/1/1995

Google Scholar

Abstract

Synthesis of 5′-amino-and 5′-azido-2′, 5′-dideoxy nucleosides from thieno [2, 3-d] pyrimidine-2, 4 (1H, 3H)-dioneSynthese von 5′-Amino-und 5′-Azido-2′, 5′-dideoxynucleosiden aus Thieno [2, 3-d] pyrimidin-2, 4 (1H, 3H)-dion ,May 1995

Publisher

Monatshefte für Chemie/Chemical Monthly

Research Type

مشترك

Date of acceptance

Publishing Date

5/1/1995

Google Scholar

Abstract

Synthesis of 3′‐Azido‐and 3′‐Amino‐2′, 3′‐Dideoxynucleosides (III)‐(V) from 2, 4‐Quinazolinediones. ,January 1995

Publisher

ChemInform

Research Type

مشترك

Date of acceptance

Publishing Date

1/17/1995

Basic Information